Cancers, Free Full-Text
Por um escritor misterioso
Descrição
Imatinib became the standard treatment for chronic myeloid leukemia (CML) about 20 years ago, which was a major breakthrough in stabilizing the pathology and improving the quality of life of patients. However, the emergence of resistance to imatinib and other tyrosine kinase inhibitors leads researchers to characterize new therapeutic targets. Several studies have highlighted the role of histone deacetylase 6 (HDAC6) in various pathologies, including cancer. This protein effectively intervenes in cellular activities by its primarily cytoplasmic localization. In this review, we will discuss the molecular characteristics of the HDAC6 protein, as well as its overexpression in CML leukemic stem cells, which make it a promising therapeutic target for the treatment of CML.
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Thoracic Cancer - Wiley Online Library
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The global burden of cancer attributable to risk factors, 2010–19: a systematic analysis for the Global Burden of Disease Study 2019 - The Lancet
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Time trial: A prospective comparative study of the time-resource burden for three-dimensional conformal radiotherapy and intensity-modulated radiotherapy in head and neck cancers – topic of research paper in Clinical medicine. Download scholarly
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Cancers, Free Full-Text
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Breast Cancer Awareness Month - National Breast Cancer Foundation
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Cancer
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Multimodal analysis of methylomics and fragmentomics in plasma cell-free DNA for multi-cancer early detection and localization
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Cancer in Lymph Nodes May Help Tumors Metastasize - NCI
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Home - Free ME from Lung Cancer
An Introduction to Human Cancers
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Cancer-immune interactions in ER-positive breast cancers: PI3K pathway alterations and tumor-infiltrating lymphocytes, Breast Cancer Research
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Sotorasib for Lung Cancers with KRAS p.G12C Mutation
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IASLC International Association for the Study of Lung Cancer
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OncLive - Clinical Oncology News, Cancer Expert Insights
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